Claudia Landwehr, Christopher Ojeda, and Oliver Tüscher ask how the effects on mental health from the Covid-19 crisis might be related to political participation. Drawing on recent studies, they find a strong relationship between the Covid-19 crisis and depressive symptoms. Holding this evidence up against US and European surveys demonstrating lower probability of voter turnout with increasing depressive symptoms, they suggest that Covid-19 may decrease political participation via declining mental health. They call for new strategies for mitigating depression’s impact on political participation and to reinvigorate participation in its aftermath.